We partner with health tech

startups to build scalable

B2B growth engines.

based in
San Francisco

B2B growth advisory and strategic capital.

In health tech, a great product alone is rarely enough. Distribution is what turns engagement into outcomes at scale.

Pistole Labs partners with a small number of health startups each year to build the commercial growth engines that generate durable, recurring revenue.

We focus on the B2B channels that matter most in this category: enterprise sales, benefits platforms, and healthcare partnerships.  

We've spent the last decade doing this work firsthand at companies like Oura, Calm, Verily, and Omada — helping take products from zero to tens of millions of lives and hundreds of millions in revenue.

We also selectively invest in startups working to translate consumer-grade design into clinical-grade health outcomes.

If you'd like to explore working together, our inbox is always open.

B2B Ventures

We partner with leadership teams to develop and launch new B2B ventures, business lines, and markets.

B2B Growth

We help companies build scalable GTM motions across enterprise sales, benefits platforms, and healthcare channels.

Strategic Capital

We selectively invest in startups building at the intersection of consumer-grade design and clinical-grade outcomes.

We’ve been lucky enough to build, advise, and invest in category-defining health tech companies.
Oura
ŌURA
Wearable biosensor that measures 50+ health biometrics
Calm
Calm
#1 app for sleep, stress, and mindfulness
Big Health
Big Health
Prescription digital therapeutics for insomnia, anxiety, and depression
Galileo Health
Galileo Health
Fully bilingual health platform offering 24/7 virtual-first care
Omada Health
Omada Health
Team-based, integrative care for chronic conditions
Anthropic
Anthropic
Safety-led AI models for healthcare and life sciences
Verily
Verily
AI-native data platform purpose-built for precision health
Kindbody
Kindbody
Leading network of tech-enabled fertility clinics
Journey Clinical
Journey Clinical
Practice management software for psychedelic-assisted therapy
Healthie
Healthie
Full-stack tech infrastructure for virtual-first care
Bryte
Bryte
Multi-sensory, adaptive smart bed sleep system
Koko
Koko
AI-powered mental health crisis detection and support
Motivo Health
Motivo Health
Virtual clinical supervision for behavioral health providers
Bright Minds
Bright Minds
Novel serotonergic therapeutics for psychiatric disorders
Simple Habit
Simple Habit
Bite-sized mindfulness for busy professionals
Forta Health
Forta Health
AI-driven personalized therapy for autism spectrum disorder
Miga Health
Miga Health
Virtual-first collaborative care for cardiometabolic health
Empower Sleep
Empower Sleep
In-network virtual sleep medicine clinic and coaching